21. DermAtlas: Online Dermatology Image Library Dermatology Image,calcinosis Cutis,s DermAtlas Dermatology Images stiff skin,scleroderma,morphea,lupus erythematosus,lupus erythematosus,lupus erythematosus,lupus erythematosus,lipoatrophy http://www.dermatlas.org/derm/result.cfm?Diagnosis=131

22. Guide To Scleroderma - Diagnosis Of Scleroderma A diagnosis of scleroderma is based largely on your medical history and findings from a physical exam. scleroderma isn t always easy to diagnose; http://arthritis.about.com/od/sclero/a/hohscleroderma_3.htm

zGCID=" test0" zGCID+=" test4" zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zDO=0 You are here: About Health Arthritis Types of Arthritis ... Scleroderma Guide To Scleroderma - Diagnosis Of Scleroderma Arthritis Health Arthritis Essentials ... Submit to Digg Related Resources - Scleroderma Scleroderma (Systemic Sclerosis) Scleroderma: Not A Single Disease Scleroderma Screening Quiz Related Resources - Scleroderma Raynaud's Phenomenon Raynaud's Phenomenon Screening Quiz Understanding Raynaud's Phenomenon Related Resources - Scleroderma Scleroderma: Test Your Knowledge An In-Depth Report: Scleroderma (Systemic Sclerosis) What Is CREST Syndrome? Most Popular Arthritis Screening Quiz Lupus Screening Quiz Fibromyalgia Screening Quiz Rheumatoid Arthritis Screening Quiz ... Osteoarthritis Screening Quiz Related Sites Senior Living Senior Health Physical Therapy Guide To Scleroderma From Your Guide to Arthritis FREE Newsletter. Sign Up Now! About.com Health's Disease and Condition content is reviewed by Kate Grossman, MD (Continued from Page 2) Part 3 of 5 - How Is Scleroderma Diagnosed? A diagnosis of scleroderma is based largely on the medical history and findings from the physical exam. Scleroderma isn't always easy to diagnose; it may take time for you and your doctor to establish a diagnosis. While having a definite diagnosis may be helpful, knowing the precise form of your disease is not needed to receive proper treatment.

23. Juvenile Scleroderma Network Organization that is working to provide educational programs about JSD, and to help children and their families to gain a better understanding. http://www.jsdn.org/

GoodSearch keywords to search for Web This Site Welcome to the Juvenile Scleroderma Network, Inc. (JSDN) A support network helping children and their families with juvenile scleroderma The JSDN is a volunteer staff made up of volunteer parents, health professionals, and people interested in Juvenile Scleroderma. Founded in 1999, the JSDN is the only national voluntary organization that works exclusively for children affected by Juvenile Scleroderma, and their families. Our mission is to provide emotional support and educational information to parents and their children living with juvenile scleroderma; to support pediatric research to identify the cause and the cure for juvenile scleroderma; to enhance the public's awareness of juvenile scleroderma and related diseases. Awareness, Support, Research... CURE Together let's keep the milestones growing until there is a cure! Make plans to attend the Juvenile Arthritis Conference, sponsored by the Arthritis Foundation. Highly Recommended by the JSDN, this symposium will include a special session focusing on juvenile scleroderma. The JSDN will be attending, so please let us know if you will be, too. It would be great to get everyone together!

24. Scleroderma In one small study, patients with localized scleroderma received 30 treatments over a period of 12 weeks. In a majority of the patients, 80% of the skin http://adam.about.com/reports/000088_10.htm

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zDO=0 You are here: About Health Health Topics A-Z Health Topics A-Z ... Help Scleroderma Article Page Navigation Introduction Symptoms Causes Risk Factors ... Resources document.getElementById(res).className = "curr"; Description An in-depth report on the causes, diagnosis, treatment, and prevention of scleroderma. Alternative Names Systemic Sclerosis Treatment for Skin Thickening Nitroglycerin is a rapidly acting nitrate and is used as an ointment (Nitro-Bid, Nitrol, Nitrong, Nitrostat) to treat hardened skin. Before applying it, any ointment that remains from the previous application should be removed. Phototherapy UVA-1 Phototherapy. Phototherapy (light therapy), specifically an approach called ultraviolet A-1 (UVA-1) radiation, is now considered the treatment of choice for local scleroderma by some experts. This treatment produces long UVA wave lengths that do not promote sunburn and may actually repair DNA in damaged skin cells. Research suggests that UVA-1 therapy blocks inflammatory immune factors and the process leading to overproliferation of collagen, addressing the underlying mechanisms of scleroderma. The procedure is effective for all stages of morphea and increases skin elasticity and, and in some cases, achieves complete clearance of symptoms. In one small study, patients with localized scleroderma received 30 treatments over a period of 12 weeks. In a majority of the patients, 80% of the skin patches disappeared or significantly improved. There were no side effects.

25. Scleroderma Clinical Trials Consortium An international organization dedicated to finding better treatment for scleroderma. http://www.sctc-online.org/

Contact Existing members: Pay dues here Welcome The 10th International Workshop on Scleroderma Research Cambridge University, Cambridge, UK August 2-6, 2008 Are you a scleroderma patient looking for support and information? See our Links page SCTC Research Study Application (Word) Online Application for Membership Latest issue! Scleroderma Care and Research journal Contact webmaster with corrections. Last update - 3/1/2008

26. Definition: Scleroderma From Online Medical Dictionary Previous sclerocorneal junction, sclerocystic disease of the ovary, sclerodactyly, scleroderm Next scleroderma, circumscribed, scleroderma, systemic, http://cancerweb.ncl.ac.uk/cgi-bin/omd?scleroderma

27. Scleroderma / Family Village Library The scleroderma Research Foundation exists as the only organization in the nation dedicated exclusively to finding a cure for this terrible disease. http://www.familyvillage.wisc.edu/Lib_scle.htm

Scleroderma Who to Contact Where to Go to Chat with Others Learn More About It Web Sites ... Search Google for "Scleroderma" Who to Contact Scleroderma Research Foundation (SRF) 220 Montgomery Street, Suite 1411 San Francisco, CA 94104 Phone: 415-834-9444 Fax: 415-834-9177 1-800-441-CURE (2873) http://www.srfcure.org/ The Scleroderma Research Foundation exists as the only organization in the nation dedicated exclusively to finding a cure for this terrible disease. Through nationwide public awareness efforts and an innovative research approach that brings together the best of business, government, science and medicine, the Foundation has raised millions of dollars for critical disease research. The mission of the Scleroderma Research Foundation is to find a cure for scleroderma, a life-threatening and degenerative illness, by funding and facilitating the most promising, highest quality research and by placing the disease and the need for a cure in the public eye. Scleroderma Foundation 300 Rosewood Drive, Suite 105

28. Health Publications Catalog Results www.4woman.gov/search/catalog. cfm?searchtype=pubtopic topic=564 Similar pages Systemic sclerosis - sclerodermaThe first detailed description of a scleroderma-like disease was published by Curzio in Naples in 1753.1 The patient, a young woman suffered from http://www.4woman.gov/search/catalog.cfm?searchtype=pubtopic&topic=564

29. Northwestern Memorial Study Tests Cancer Drug On Scleroderma Patients Physicians at Northwestern Memorial Hospital are studying the effects of an anticancer drug to treat patients with scleroderma, a rare, http://www.medicalnewstoday.com/articles/99799.php

@import "/css/pagelayout.css"; @import "/css/default.css"; @import "/css/defaultnews.css"; Health News Health Videos Forum Advertise ... Contact News Archive [ link Web Wikipedia Medical Dictionary [ link Immune System / Vaccines News Useful Links Northwestern Memorial Study Tests Cancer Drug On Scleroderma Patients Main Category: Immune System / Vaccines Also Included In: Arthritis Cardiovascular / Cardiology Neurology / Neuroscience Article Date: 07 Mar 2008 - 0:00 PDT email to a friend printer friendly view / write opinions rate article Current Article Ratings: Patient / Public: 4 (2 votes) Health Professional: 5 (2 votes) Article Opinions: 0 posts Physicians at Northwestern Memorial Hospital are studying the effects of an anti-cancer drug to treat patients with scleroderma, a rare, incurable autoimmune rheumatic disease that leads to hardening and tightening of the skin and connective tissues. Scleroderma affects an estimated 300,000 people in the United States and can often attack the lungs, heart, kidneys and intestinal tract, and sometimes lead to death. The study is the first of its kind to examine if Gleevec , a cancer drug commonly used to treat leukemia, will treat the skin thickness in scleroderma patients by blocking the pathway that causes fibrosis. Patients enrolled in the clinical trial will receive daily oral doses of Gleevec for six months and will be evaluated initially on a weekly basis at Northwestern Memorial, one of only three centers nationwide participating in the study. Others include Johns Hopkins and Boston University Medical Center.

30. Scleroderma - Signs And Symptoms It is caused by scleroderma and not by too much calcium in your diet. The lumps occasionally break through the skin and leak a chalky, white material. http://www.ucsfhealth.org/adult/medical_services/arthritis/scleroderma/condition

University of California, San Francisco About UCSF UCSF Children's Hospital Search Welcome Hospitals and Clinics Appointments Billing ... Other Resources Scleroderma Scleroderma Signs and Symptoms Diagnosis Treatment Signs and Symptoms Scleroderma can affect everyone differently. The following are some of the general symptoms associated with the condition. Skin changes , including: Hardening or thickening of your skin, particularly on your hands, arms and face, and occasionally on your trunk and legs Loss of hair over the affected area Change in skin color Ulcers or sores on your fingers Swelling or puffiness in your hands or feet , often occurring in the morning. Sclerodactyly means shortening of the skin of the fingers and toes. This usually occurs after the initial swelling goes away. You may experience: Skin on your fingers and toes becoming hard and shiny Difficulty bending your fingers Raynaud's Phenomenon , a condition associated with poor blood flow to fingers and toes. Blood flow decreases because blood vessels in these areas become narrow for a short time in response to cold or emotional stress. Raynaud's Phenomenon may cause: Your fingers, toes, tips of your ears, nose or tongue to be very sensitive to cold

31. Sclero There is so much to say about scleroderma and each child’s case is so different Often children are not recognized to have scleroderma until they develop http://www.goldscout.com/sclero.html

id=13897 Scleroderma and related conditions This page is provided by Thomas J. A. Lehman MD Delivering the best care - with great care Dr. Lehman is the author of many textbook chapters and articles on the care of children and young adults with scleroderma. He practices in New York City Click here for more information about Dr. Lehman or the Hospital for Special Surgery. This information is provided as a public service. No warranty is expressed or implied. Being told that your child has scleroderma is a very scary experience The first thing you need to know is what type of scleroderma. Sometimes doctors use the word scleroderma when they are referring to localized lesions of morphea (see below). This isn’t pretty to look at, but it is rarely serious. Other times a child has linear scleroderma with an area of tight skin on an arm or leg. Again, this isn’t pretty, but it isn’t life threatening. Other children have progressive systemic sclerosis or CREST syndrome. These are the more severe forms of scleroderma that may be life-threatening. Before you do anything else make sure you know which form of scleroderma the doctor is talking about.

32. InteliHealth: scleroderma is a poorly understood illness that causes widespread hardening of the skin, scleroderma also is called progressive systemic sclerosis. http://www.intelihealth.com/IH/ihtIH/WSIHW000/9339/31054.html

chrome_imgPreload('gifChr_mid_but_home_mo_1','http://www.intelihealth.com/i/C/Chr_mid_but_home-o.gif'); chrome_imgPreload('gifChr_mid_but_comm_mo_2','http://www.intelihealth.com/i/C/Chr_mid_but_comm-o.gif'); chrome_imgPreload('gifChr_mid_but_dental_mo_3','http://www.intelihealth.com/i/C/Chr_mid_but_dental-o.gif'); chrome_imgPreload('gifChr_mid_but_drug_mo_4','http://www.intelihealth.com/i/C/Chr_mid_but_drug-o.gif'); chrome_imgPreload('gifChr_mid_but_askexpert_mo_5','http://www.intelihealth.com/i/C/Chr_mid_but_askexpert-o.gif'); chrome_imgPreload('gifChr_mid_but_medical_mo_6','http://www.intelihealth.com/i/C/Chr_mid_but_medical-o.gif'); chrome_imgPreload('gifchr_mid_but_news_mo_7','http://www.intelihealth.com/i/c/chr_mid_but_news-o.gif'); chrome_imgPreload('gifChr_mid_but_privacy_mo_8','http://www.intelihealth.com/i/C/Chr_mid_but_privacy-o.gif'); chrome_imgPreload('gifChr_mid_but_SiteMap_mo_9','http://www.intelihealth.com/i/C/Chr_mid_but_SiteMap-o.gif'); Scleroderma What Is It? Symptoms Diagnosis Expected Duration ... Additional Info What Is It? Scleroderma is a poorly understood illness that causes widespread hardening of the skin, especially on the hands and face. It also can damage the lungs, heart, kidneys, digestive tract, muscles and joints. It is a long-lasting (chronic) autoimmune disorder, an illness in which the body's immune defenses mistakenly attack the body's own cells rather than protecting them from outside invaders. Scleroderma also is called progressive systemic sclerosis.

33. Localized Scleroderma Morphea scleroderma means hard skin and is pronounced sklero-derma. scleroderma is a disease that causes fibrosis (hardening) of the skin and sometimes the http://www.skinsite.com/info_scleroderma_localized.htm

Localized Scleroderma I. Definition: Scleroderma means "hard skin" and is pronounced skler-o-derma. Scleroderma is a disease that causes fibrosis (hardening) of the skin and sometimes the internal organs. Scleroderma can range from a form localized to the skin to a severe disease the effects the internal organs known as systemic scleroderma. Localized scleroderma can range from just a few spots on the skin to covering almost the entire skin surface. The skin lesions of localized scleroderma feel firm and hard. The color is ivory to yellowish in color. The skin lesions of localized scleroderma are usually seen on the trunk but can also occur on the face, arms, and legs. Localized scleroderma may last for a few months to many years. The condition is four times more common in women and usually starts between the ages of twenty and fifty. II. Cause: The cause of scleroderma is unknown. III. Treatment: There is not a known medication that will stop or reverse the process of scleroderma. Milder forms of scleroderma may be helped by topical cortisone medications or cortisone injections.

34. BBC - Health - Conditions - Scleroderma The affects of scleroderma and how it can be treated. http://www.bbc.co.uk/health/conditions/scleroderma1.shtml

@import '/includes/bbcpage/v3-0/toolbar.css'; Skip to main content Text Only version of this page Access keys help Home Explore the BBC 29 May 2008 Accessibility help Text only BBC Homepage Lifestyle ... Contact Us Like this page? Send it to a friend! Scleroderma Dr Rob Hicks Scleroderma - from the Greek words for 'hard' and 'skin' - is an autoimmune disease that targets the connective tissue found in the skin, muscles and organs. In this article What's the cause? What are the symptoms? Who's affected? What's the treatment? ... Advice and support What's the cause? The immune system that should protect the body attacks it instead In autoimmune diseases, the immune system that should protect the body attacks it instead. In this case, it causes inflammation and scarring, which eventually leaves skin thickened, muscles weakened and organs damaged. No one really knows what causes scleroderma, although it's thought that certain genes may be involved in the changes that occur around the body as the disease develops. What are the symptoms? There are many forms of scleroderma, but the main two are localised scleroderma, which affects just the skin, and systemic sclerosis, which also affects the internal organs.

35. Health Effects Of Occupational Exposure To Respirable Silica - April 2002 B scleroderma (progressive systemic sclerosis). A rare multisystem disorder characterized by inflammatory, vascular, and fibrotic changes usually involving http://www.cdc.gov/Niosh/02-129B.html

NIOSH HAZARD REVIEW Health Effects of Occupational Exposure to Respirable Crystalline Silica Table of Contents Abbreviations back ACGIH American Conference of Governmental Industrial Hygienists AMG alpha-1-microglobulin ATS American Thoracic Society BAL bronchoalveolar lavage BMG beta-1-microglobulin BMI body mass index degree(s) Celsius CA chromosomal aberration(s) cc cubic centimeter CDC Centers for Disease Control and Prevention CEN European Standardization Committee CFR Code of Federal Regulations CI confidence interval cm centimeter(s) COC census occupation code COPD chronic obstructive pulmonary disease Cu copper CV coefficient of variation CV pooled coefficient of variation CWP coal workers pneumoconiosis DE diatomaceous earth DLCO diffusing capacity of the lung for carbon monoxide DNA deoxyribonucleic acid EPA U.S. Environmental Protection Agency degree(s) Fahrenheit FEV forced expiratory volume in 1 second FVC forced vital capacity g gram(s) HIV human immunodeficiency virus HLA human leukocyte antigen hprt hypoxanthine-guanine phosphoribosyl transferase hr hour(s) HSE Health and Safety Executive (United Kingdom) HVLV high-velocity/low-volume IARC International Agency for Research on Cancer ICD-9 International Classification of Diseases, 9th edition

36. Scleroderma Association Of NSW The scleroderma Association Of NSW inc. was established in 1979. The Association s aim is to provide support and information to people with scleroderma, http://www.sclerodermansw.org/

Scleroderma Association of NSW The Scleroderma Association of NSW Inc. cannot offer direct advice on treatment or available therapies. It is up to each patient to make all relevant health decisions In consultation with their own doctor or health professional. Home Contact Us Our Pamphlets are free What is scleroderma From our Newsletters ... Guest Book Our membership fees are $23.00 per year and entitles members to our extensive information and four newsletters per year. Download membership form here: rtf or pdf Please print them, then fill in and post to: P0 Box 227 ASHFIELD NSW 1800 Donations Tax deductible donations to the Association's Research Fund can be made by forwarding a cheque to: Donations of $2 or more are Tax deductible. Her Excellency Prof. Marie Bashir has graciously agreed to become our Patron. Group Profile and Structure Management Committee Medical Advisory Panel Management of Volunteers Group Profile and Structure The Scleroderma Association Of NSW inc. was established in 1979. The Association's aim is to provide support and information to people with scleroderma, their carers, and interested professionals by offering: seminars

37. For Some Patients, Scleroderma Runs Deep Although skin hardening is the most obvious sign of scleroderma, it is by no means the most dangerous The disease can cause lifethreatening problems in http://healthlink.mcw.edu/article/1031002255.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: Skin/Dermatology Immune Disorders Musculoskeletal Disorders By keywords: scleroderma connective tissue diseases Autoimmune Diseases Skin Diseases ... rheumatic diseases Receive Health Link via email! Subscribe now >> For Some Patients, Scleroderma Runs Deep The term ‘scleroderma’ comes from the Greek words for ‘hard skin’,” says M. E. Csuka, MD , Associate Professor of Medicine at the Medical College of Wisconsin. “Its most obvious manifestation is thickening and hardening of the skin, and that’s how we usually make the diagnosis.” Although it’s the most obvious sign of scleroderma, skin hardening is by no means the most dangerous symptom of this baffling disease. Patients who have this thickened, hard skin experience decreases in physical functioning and limits in the activities of daily living. But for the most part this skin problem is not what causes them their most serious morbidity and mortality,” says Dr. Csuka. In fact the disease can run much deeper and cause life-threatening problems in the lungs, heart, esophagus, gastrointestinal tract and kidneys. According to the Scleroderma Foundation, an estimated 300,000 people in the United States have the disease. Women are about four times more likely than men to develop scleroderma, which is considered both a rheumatic disease and a connective tissue disease. Rheumatic diseases are characterized by inflammation and pain in the muscles, joints or fibrous tissue. A connective tissue disease affects the major substances in the skin, tendons and bones.

38. Scleroderma - WrongDiagnosis.com scleroderma information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis. http://www.wrongdiagnosis.com/s/scleroderma/intro.htm

About Us Boards Bookmark this page HOME ... External links relating to Scleroderma RESEARCH Search the latest treatment information here. Choose... Asthma Allergies Breast Cancer Cancer Diabetes Headache Heartburn Heart Disease High Cholesterol Hypertension Migraine Reflux Thyroid Disease All Diseases... Dr. Huntley's Diagnosis Checklist Have a symptom? See what questions a doctor would ask. Choose... Rash Fever Pain Headache Fatigue Diarrhea All checklists Next Diseases Scleroderma Scleroderma Contents: Scleroderma Introduction: Scleroderma Full Text Books Online Symptoms Misdiagnosis ... Full Contents list Introduction: Scleroderma Scleroderma: Derived from the Greek words "sklerosis," meaning hardness, and "derma," meaning skin, scleroderma literally means hard skin. Though ... more about Scleroderma Scleroderma: A rare, progressive connective tissue disorder involving thickening and hardening of the skin and connective tissue. There are a number of forms of scleroderma with some forms being systemic (involving internal organs). More detailed information about the symptoms causes , and treatments of Scleroderma is available below.

39. Scleroderma World SD World is a list dedicated to providing a place where those who suffer from scleroderma and other autoimmune problems may gather in a warm, friendly forum http://www.sdworld.org/

SD World is a list dedicated to providing a place where those who suffer from Scleroderma and other autoimmune problems may gather in a warm, friendly forum for an upbeat, open and free exchange of thoughts, ideas and information. We also offer a section of links for scleroderma medical, support, health or fun information. Email List SD World is an email list dedicated to providing a place where those who suffer from Scleroderma and other autoimmune problems may gather in a warm, friendly forum for an upbeat, open and free exchange of thoughts, ideas and information. Click to subscribe SD Round the World SD Round the World These pages Links, Links, Links Links, Links, Links . Are you interested in more information? The internet is a really wonderful source. Here are some links to a few excellent medical and/or informational sites.

40. Scleroderma Citrinum (MushroomExpert.Com) Some authors call the mushrooms in scleroderma earthballs, to emphasize their differences from fleshier puffballs. Many scleroderma species have tough http://www.mushroomexpert.com/scleroderma_citrinum.html

Major Groups Scleroderma Scleroderma citrinum Scleroderma citrinum Basidiomycetes > Boletales > Sclerodermataceae > Scleroderma by Michael Kuo This puffball and its relatives have been the source of tremendous confusion recently, due to the revelation that they are closely related to boletes , especially those in Gyroporus . For more information on this odd twist of events, see this article Some authors call the mushrooms in Scleroderma "earthballs," to emphasize their differences from fleshier puffballs. Many Scleroderma species have tough outer rinds, and Scleroderma citrinum has a rind that is scaly and hard. When sliced, the rind stains pinkish. Inside, the spore mass is initially white, but soon begins to turn dark purple to purple-black, from the center outwards. Scleroderma citrinum is poisonous, causing nausea, vomiting, and diarrhea. Sadly, I know this from personal experience; I once consumed a large quantity of blueberries that I had picked near a large fruiting of Scleroderma . I forgot to wash themrather unfortunately, since before picking the berries, I spent a good ten minutes stomping on earthballs to demonstrate to a friend how the spores were distributed. The berries (and my clothes, my shoes . . . ) were covered with a thick spore dust. How I managed not to notice this dust when I chowed down on the berries, I'll never knowbut I spent two days regretting my stupidity. Another little Scleroderma citrinum tidbit: it is the only mushroom that plays host to Boletus parasiticus , an extremely odd little bolete that actually parasitizes this puffball. See the illustration to the right. Go figure!

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