41. Scleroderma --  Britannica Online Encyclopedia Britannica online encyclopedia article on scleroderma a chronic disease of the skin that also can affect the blood vessels and various internal organs. http://www.britannica.com/eb/article-9066307/scleroderma

var britAdCategory = "other"; Already a member? LOGIN Encyclopædia Britannica - the Online Encyclopedia Home Blog Advocacy Board ... Free Trial Britannica Online Content Related to this Topic This Article's Table of Contents scleroderma Print this Table of Contents Linked Articles collagen autoimmune Shopping New! Britannica Book of the Year The Ultimate Review of 2007. 2007 Britannica Encyclopedia Set (32-Volume Set) Revised, updated, and still unrivaled. New! Britannica 2008 Ultimate DVD/CD-ROM The world's premier software reference source. scleroderma Page 1 of 1 a chronic disease of the skin that also can affect the blood vessels and various internal organs. Scleroderma is characterized by excessive deposition of collagen scleroderma... (75 of 521 words) To read the full article, activate your FREE Trial Close Enable free complete viewings of Britannica premium articles when linked from your website or blog-post. Now readers of your website, blog-post, or any other web content can enjoy full access to this article on scleroderma , or any Britannica premium article for free, even those readers without a premium membership. Just copy the HTML code fragment provided below to create the link and then paste it within your web content. For more details about this feature, visit our Webmaster and Blogger Tools page Copy and paste this code into your page var dc_UnitID = 14; var dc_PublisherID = 15588; var dc_AdLinkColor = '009900'; var dc_adprod='ADL'; var dc_open_new_win = 'yes'; var dc_isBoldActive= 'no';

42. Eustar - Eular Scleroderma Trials And Research eular scleroderma trials and research. EUSTAR aims to foster the awareness, understanding and research of scleroderma and its management throughout http://www.eustar.org/

@import url("themes/eustar/style/style.css"); QBPATH='/javascript'; VISUAL=0; SECURE=1; eustar eular scleroderma trials and research May 29, 2008 Login Search Impressum welcome ... eular Page Hits: Welcome to EUSTAR The EULAR Scleroderma Trials and Research group (EUSTAR) EUSTAR aims to foster the awareness, understanding and research of scleroderma and its management throughout Europe. EUSTAR 2nd Educational Course in Bad Nauheim EUSTAR secretariat EUSTAR Executive Secretariat Department of Medicine Section of Rheumatology Villa Monna Tessa Viale Pieraccini 18 50139 Florence, Italy Tel: +39 055 7949271 Fax: +39 055 7949271 E-Mail: cerinic@unifi.it eustar@unifi.it "EULAR/EUSTAR Recommendations on the treatment of Systemic Sclerosis. See the group at work and the poster to be presented during the EULAR Annual Congress in Barcelona, June 2007" webmaster - Visitor hits: 19369

43. Log In Problems Is the PAH that is associated with scleroderma the same as IPAH, and is anticoagulation a useful therapy? http://www.medscape.com/viewarticle/570806

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44. Scleroderma Prevention, Cure, Curing Protocol, Remedies, Herbs, Alternative Medi This scleroderma Prevention and/or Curing Protocol is for people who are ready to take the full responsibility for their own health. http://www.curezone.com/dis/1.asp?C0=300

45. Scleroderma scleroderma is a chronic, progressive disease that causes the skin and connective tissue to thicken and become tight and hard. Connective tissue is found http://www.hmc.psu.edu/healthinfo/s/scleroderma.htm

46. Scleroderma / Systemic Sclerosis By Drdoc On-line scleroderma / systemic sclerosis by drdoc online. http://www.arthritis.co.za/scleroderma.htm

Scleroderma / Systemic sclerosis by drdoc on-line Table of contents Definition and Epidemiology Musculoskeletal involvement in Scleroderma Classification Renal disease in Scleroderma ... Go to Arthritis index page Systemic sclerosis is a generalized disorder of connective tissue, leading to progressive tissue fibrosis. The condition characterized by fibrosis of the skin, but with involvement also of joints, tendons, muscles, and internal organs The condition was first described by Curzio in the 1753. Initially it was seen as a condition affecting the Skin but in 1945, Goetz proposed a description of progressive systemic sclerosis. He described visceral lesions in autopsy cases, whilst studying Medicine and forensic pathology at the University of Cape Town, South Africa. In addition, a limited Scleroderma was described in 1964 by Winterbauer. He referred to a syndrome with calcinosis raynauds phenomenon esophageal dysmotility sclerodactyly , and Telangiectasia . This subsequently became known as the C R E S T syndrome.

47. OMIM - SCLERODERMA, FAMILIAL PROGRESSIVE MIM %181750 Text See Also References Contributors Creation Date Edit History Clinical Synopsis. http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=181750

48. Scleroderma Important It is possible that the main title of the report scleroderma is not the name you expected. Please check the synonyms listing to find the alternate http://arthritis.webmd.com/scleroderma-10633

var s_furl = "/scleroderma-10633"; var image_server_url = "http://img.webmd.com/dtmcms/live"; var priTopId = "4271"; var secTopId = ""; document.write(wmd_today); Bookmark This Page Site Map Sign up for WebMD Newsletters WebMD Home ... Pill Identifier document.write(''); Women's Health Home Balance Fitness Parenting ... Pregnancy document.write(''); Men's Health Home Balance Fitness Parenting document.write(''); Children's Health Home Fitness Parenting Pregnancy ... Arthritis Health Center Email a Friend Print Article Arthritis Health Center Font Size A A A Scleroderma Important It is possible that the main title of the report Scleroderma is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Progressive Systemic Sclerosis PSS Sclerosis, Familial Progressive Systemic Systemic Sclerosis Disorder Subdivisions Morphea Linear Scleroderma CREST Syndrome General Discussion Scleroderma is a rare autoimmune connective tissue disorder characterized by abnormal thickening of the skin. Connective tissue is composed of collagen, which supports and binds other body tissues. There are several types of scleroderma. Some types affect certain, specific parts of the body, while other types can affect the whole body and internal organs (systemic). Scleroderma is also known as progressive systemic sclerosis. The exact cause of scleroderma is unknown. Resources Scleroderma Research Foundation 220 Montgomery Street

49. Scleroderma Links to information and resources for scleroderma, including CREST Syndrome. http://rarediseases.about.com/cs/scleroderma/

zOBT=" Ads" zGCID=" test1" zGCID+=" test9" zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zDO=0 z160=zpreC(160,600);z336=zpreC(336,280);z728=zpreC(728,90);z155=zpreC(336,155);zItw=160 Search Rare Diseases var h2=document.getElementsByTagName("h2")[0];if(h2.getElementsByTagName("a")[0].firstChild.nodeValue.length>28)h2.className="long"; Home Health Rare Diseases Email ... Research More from About.com Browse Rare Diseases Is it a Rare Disease? Information by Disease Type Rare Diseases A - B Rare Diseases C - D ... Topics A-Z Search Scleroderma page Guide picks Progressive systemic sclerosis (hardening) which shows on the skin as tightness, firmness, and swelling, and limited movement. Includes CREST Syndrome. Scleroderma in Southie For Liz Lombard, having scleroderma seemed unusual. But after talking to other people who lived in South Boston, she found that the usually rare disorder was occurring throughout the neighborhood. Her advocacy prompted the start of a local study. Article from the About.com Guide to Rare/Orphan Diseases. AARDA: Scleroderma Choose "Scleroderma" from the drop-down menu for brief information from the American Autoimmune Related Diseases Association. You can also order a packet of information.

50. Scleroderma Registry - Full Text View - ClinicalTrials.gov clinicaltrials.gov/ct/show/NCT00074568 Search of Open Studies scleroderma, Systemic - List Results 13, Recruiting, Efficacy and Safety of Imatinib in scleroderma 15, Recruiting, Pulmonary Involvement in scleroderma A Clinical Study of the Safety and http://clinicaltrials.gov/ct/show/NCT00074568

Home Search Study Topics Glossary Full Text View Tabular View Contacts and Locations Related Studies Scleroderma Registry This study is currently recruiting participants. Verified by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), March 2008 Sponsors and Collaborators: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) The University of Texas Health Science Center, Houston Information provided by: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) ClinicalTrials.gov Identifier: Purpose Scleroderma is likely caused by a combination of factors, including an external trigger (infection or other exposure) and a genetic predisposition. The Scleroderma Registry will conduct genetic analyses for disease-related genes in patients with scleroderma and their family members (parents, brothers, and sisters). Condition Systemic Sclerosis Scleroderma MedlinePlus related topics: Scleroderma U.S. FDA Resources

51. Uhrad.com - Musculoskeletal Imaging Teaching Files Case Forty Eight Systemic Sclerosis (scleroderma) Discussion Progressive systemic sclerosis (scleroderma) is a disorder of connective tissue http://www.uhrad.com/msiarc/msi048.htm

uhrad.com - Musculoskeletal Imaging Teaching Files Case Forty Eight - Systemic Sclerosis (Scleroderma) (Image #1 and Image #2) (Image #3 and Image #4) Click On Images for Enlarged View Clinical History: Not given. Findings: Image #1 is a plain film of the hand demonstrating acroosteolysis of the distal tufts of the bilateral fourth and fifth distal phalanges. Image #2 is a plain film of the hands in a second patient with the same diagnosis demonstrating acroosteolysis as well as flexion contractures. Image #3 is a PA chest x-ray demonstrating mild basilar interstitial prominence as well as calcifications projecting over the left shoulder soft tissues. Image #4 is a plain film of the pelvis demonstrating extensive soft tissue calcifications. Diagnosis: Systemic sclerosis (scleroderma). Discussion: Progressive systemic sclerosis (scleroderma) is a disorder of connective tissue dysfunction which affects whole organ systems including skin, lungs, GI, heart, kidneys and musculoskeletal. The characteristic radiographic presentation is generally defined as soft tissue atrophy, calcifications, and distal phalangeal resorption in the hand. In addition, recently described findings include erosion involving the distal interphalangeal disease (DIP) and less commonly proximal interphalangeal (PIP) joints. Although there has been no definite pathogenesis identified, it is felt that progressive systemic sclerosis secondary to a structural defect in the microvasculature. This is supported by the fact that there are often vascular changes identified in multiple tissues.

52. Scleroderma Video A collection of 11 video presentations made by some of the foremost scleroderma experts in the US. http://www.starlight-productions.com/scleroderma_video_series.htm

Home V i deo Titles ... About Scleroderma Scleroderma Video Series 11 Video Volumes available VHS Video Cassettes: $19.95 each The Scleroderma Video Series is a collection of presentations made by some of the foremost Scleroderma experts in the United States, including Rheumatologists, Cardiologists, Surgeons, Dieticians, Occupational Therapists, Dermatologists, Psychologists, Researchers and more. Topics have included: Overview and causes of Scleroderma Scleroderma Therapies Raynauds Phenomenon Genetics ... Drug Interactions much more Among the speakers that appear within the Scleroderma Video series are eminent experts in the field, including: Philip Clements, MD Daniel Furst, MD Sergio Jimenez, MD Maureen Mayes, MD James Seibold, MD Fredrick Wigley, MD For a complete listing of available titles, please click here Since 1994, Starlight Productions has produced over 30 videos directly related to Scleroderma. As we continue to videotape new presentations, we revise our offerings so that topic duplication is avoided, and outdated presentations are removed. Scleroderma Information - More than our business Our involvement with Scleroderma began as a commercial shoot in 1994. A previous client who had employed us for another type of service happened to be a Scleroderma patient, and a Chapter President within the former United Scleroderma Foundation. She requested our services for their annual chapter medical workshop, and, liking the results, recommended us the National Foundation for the 1995 USF National Conference.

53. American Society For Scleroderma Research ASFSR brings people together, to work together, to raise funds to find a cure for scleroderma. Find information about this autoimmune disease, http://asfsr.org/

Dates To Remember What is Scleroderma? We have several fantastic events coming up! Something for everyone to enjoy! Please mark your calendar now so you don't miss out! More details to follow. August 4 thru 8, 2008 The International Workshop on Scleroderma Research http://www.sclerodermaworkshop.org/ ASFSR is a proud Corporate Sponsor of an international symposium taking place in the United Kingdon this fall. The International Workshop on Scleroderma Research will be held at Trinity College in Cambridge, England, from August 4 thru 8, 2008. It is a biennial event that will be attended by researchers and physicians from around the world. The conclave is specifically designed to share knowledge and information and to further research efforts as to the cause and a cure for this disease. October 12, 2008 5 K Walk - Lake Side Wolf Park Great Hollow Lake 454 Purdy Hill Road Monroe, CT November 8, 2008 5th Annual Dinner Liedle's Catering Hall Stratford, CT "Joey and Maria's Comedy Italian Wedding" Full night of fun starting at 6:00 - 10:00 PM Cocktail Hour 6 - 7 PM Tickets - $50.00 per person -

54. Scleroderma - CNN.com scleroderma (sklereo-DER-muh) is a rare, progressive disease that leads to hardening and tightening of the skin and connective tissues — the fibers that http://www.cnn.com/HEALTH/library/DS/00362.html

@import url(http://i.cdn.turner.com/cnn/.element/css/2.0/common.css); var cnnCurrTime = new Date(1212072622718); var cnnCurrHour = 10; var cnnCurrMin = 50; var cnnCurrDay='Thu'; @import url(/HEALTH/library/healthlibrary.css); Home World U.S. Politics ... International Edition In association with: HEALTH/LIBRARY Bones/Joints/Muscles Juvenile rheumatoid arthritis Osteoarthritis Rheumatoid arthritis Bursitis ... Greenstick fractures INFORMATION CENTERS: Pick a category Health Centers Family Health Men's Health Women's Health Children's Health Seniors' Health Working Life Pain Management Condition Centers Immune System Allergy Alzheimer's Arthritis Respiratory System Cancer Endocrine System Digestive System Heart and Blood Infectious Disease Mental Health Note: All links within content go to MayoClinic.com Diseases and Conditions Scleroderma From MayoClinic.com Special to CNN.com Introduction In some cases, scleroderma also affects the blood vessels and internal organs. Scleroderma is one of a group of arthritic conditions called connective tissue disorders. In these disorders, a person's antibodies are directed against his or her own tissues. Researchers haven't established a definitive cause for scleroderma. It's more common in women than in men and more common in adults than in children. Scleroderma can run in families, but in most cases it occurs without any known family tendency for the disease. Scleroderma isn't considered contagious or cancerous, but this chronic condition can greatly affect self-esteem and the ability to accomplish everyday tasks.

55. Definition Of Scleroderma - NCI Dictionary Of Cancer Terms A chronic disorder marked by hardening and thickening of the skin. scleroderma can be localized or it can affect the entire body (systemic). http://www.nci.nih.gov/Templates/db_alpha.aspx?CdrID=44142

56. University Of Michigan Scleroderma Program Home Page The University of Michigan scleroderma Program is a multidisciplinary group of care givers, scientists and clinical researchers dedicated to advancing http://www.med.umich.edu/scleroderma/index.htm

UMHS HOME SCLERODERMA PROGRAM Division of Rheumatology Search this site About Us Faculty Research Learn About Scleroderma ... Internal Medicine Divisions Welcome! The University of Michigan S cleroderma Program The University of Michigan Scleroderma Program is a multidisciplinary group of care givers, scientists and clinical researchers dedicated to advancing knowledge about scleroderma and related conditions. The overarching goal of the Program is to develop effective therapies for the disease and its complications. CORE elements are: C linical care with emphasis on cost-effective outpatient management O utreach to the community of patients and physicians R esearch into the cause, mechanisms and treatment E ducation of physicians and allied health professionals A. Alfred Taubman Health Care Center Contact Information: University of Michigan Scleroderma Program Domino's Farms 24 Frank Lloyd Wright Drive P.O. Box 481, Lobby M

57. NEJM -- Cyclophosphamide Versus Placebo In Scleroderma Lung Disease Methods At 13 clinical centers throughout the United States, we enrolled 158 patients with scleroderma, restrictive lung physiology, dyspnea, and evidence http://content.nejm.org/cgi/content/abstract/354/25/2655

// var NTPT_PGEXTRA = ''; // var NTPT_PGREFTOP = false; // var NTPT_NOINITIALTAG = false; CM8ShowAd("Topbanner"); FREE NEJM E-TOC HOME SUBSCRIBE CURRENT ISSUE ... COLLECTIONS Search Term Advanced Search Sign in Subscribe Previous Volume 354:2655-2666 June 22, 2006 Number 25 Next Cyclophosphamide versus Placebo in Scleroderma Lung Disease Donald P. Tashkin, M.D., Robert Elashoff, Ph.D., Philip J. Clements, M.D., M.P.H., Jonathan Goldin, M.D., Ph.D., Michael D. Roth, M.D., Daniel E. Furst, M.D., Edgar Arriola, Pharm.D., Richard Silver, M.D., Charlie Strange, M.D., Marcy Bolster, M.D., James R. Seibold, M.D., David J. Riley, M.D., Vivien M. Hsu, M.D., John Varga, M.D., Dean E. Schraufnagel, M.D., Arthur Theodore, M.D., Robert Simms, M.D., Robert Wise, M.D., Fredrick Wigley, M.D., Barbara White, M.D., Virginia Steen, M.D., Charles Read, M.D., Maureen Mayes, M.D., Ed Parsley, D.O., Kamal Mubarak, M.D., M. Kari Connolly, M.D., Jeffrey Golden, M.D., Mitchell Olman, M.D., Barri Fessler, M.D., Naomi Rothfield, M.D., Mark Metersky, M.D., for the Scleroderma Lung Study Research Group Full Text PDF PDA Full Text PowerPoint Slide Set ... by Martinez, F. J.

58. NIH - Scleroderma Handout on Health scleroderma PDF Version . contact number Call (877) 22NIAMS or (301) 495-4484 for more information http://health.nih.gov/result.asp/581

Employee Info Staff Directory Health Information Spotlight Email this page ... Browse Health Topics Alphabetically Scleroderma Quick Links Men's Health Minority Health Seniors' Health Women's Health Search Health Topics Health Topics A-Z A B C D ... X Y Z See All Topics NIAMS National Institute of Arthritis and Musculoskeletal and Skin Diseases Handout on Health: Scleroderma PDF Version ] Call (877) 22-NIAMS or (301) 495-4484 for more information Related Topics Raynaud's Disease Immune System Skin, Hair, and Nails ^ top On This Page: NIAMS MedlinePlus Clinical Trials Information The NIH funds research studies that you may be able to join. Visit clinicaltrials.gov for a list of ongoing clinical trials. This page was last reviewed on Friday, July 27, 2007. Contact Us Privacy Notice Accessibility Site Map ... FAQ National Institutes of Health (NIH) 9000 Rockville Pike Bethesda, Maryland 20892 Department of Health and Human Services

59. Epidemiology Of Scleroderma. Increased frequency of B8/DR3 in scleroderma and association of the haplotype with impaired cellular immune response. Clin Exp Immunol. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1033319

60. Scleroderma The scleroderma (Systemic Sclerosis) Center at The Boston Medical Center (Boston University School of Medicine) is a collaboration of the Pulmonary and http://www.bumc.bu.edu/Dept/Content.aspx?DepartmentID=435&PageID=10782

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