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64. Sickle Cell Anemia : Guidelines, Reviews, Statements, Recommendations, Standards Obstetrics, gynecology and reproductive medicine guidelines. Anemia and hemoglobinopathies. PubMed Free Full Text Français Español - Italiano - Deutsch http://www.gfmer.ch/Guidelines/Anemia_and_hemoglobinopathies/Sickle_cell_anemia.

Obstetrics, gynecology and reproductive medicine guidelines Anemia and hemoglobinopathies PubMed Free Full Text Français - Español - Italiano ... - Deutsch Sickle cell anemia International - United Kingdom - United States of America - WHO ... - Articles in journals International Cochrane Library Splenectomy versus conservative management for acute sequestration crises in people with sickle cell disease [2008] Psychological therapies for sickle cell disease and pain [2008] Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease [2008] ... Blood transfusion for preventing stroke in people with sickle cell disease [2008] United Kingdom British Society for Haematology Guidelines for the Management of Acute Painful Crisis in Sickle Cell Disease [2003] GenePool Sickle Cell Anaemia [2006] ... Sickle cell disease screening (in newborns) [2006] United States of America American Academy of Pediatrics Health Supervision for Children With Sickle Cell Disease [2002] American College of Obstetricians and Gynecologists Is Hormonal Contraceptive Use Safe for Women with Sickle Cell Disease? [2000] ... Penicillin Prophylaxis Can Be Safely Discontinued in Children With Sickle Cell Anemia After Age 5 [1998] WHO World Health Organization Sickle-cell disease and other haemoglobin disorders [2006] Sickle-cell anaemia [2006] Articles in journals American Family Physician Opportunities to Improve Outcomes in Sickle Cell Disease [2006] Sickle Cell Disease in Childhood: Part II. Diagnosis and Treatment of Major Complications and Recent Advances in Treatment [2000]

65. Open Site - Health: Conditions And Diseases: Blood Disorders: Anemia: Sickle Cel General Information. Sickle cell anemia (SCA) is an autosomal recessive disorder that affects the structure of hemaglobin (Hb). In low oxygen levels, http://open-site.org/Health/Conditions_and_Diseases/Blood_Disorders/Anemia/Sickl

Enter your search terms Submit search form Web open-site.org home log in apply to edit help ... Anemia : Sickle Cell Anemia history General Information Sickle cell anemia (SCA) is an autosomal recessive disorder that affects the structure of hemaglobin (Hb). In low oxygen levels, the mutant hemaglobin molecules clump and the red blood cells (RBC) are deformed into a sickle-like shape. This differs from their normal doughnut shape. Sickle cell RBCs become trapped in capillary walls, causing pain and possibly damaging organs. Although this disease can affect practically any ethnicity, sickle cell anemia predominantly occurs in the African-American population. One in ten African-Americans is a carrier of the defective gene. history Disease Etiology SCA arises from a missense mutation (glutamine to valine) in residue 6 of the beta subunit of hemoglobin. The nonpolarity of valine, located on in a normally exposed region of the molecule, favors hydrophobic interactions with phenylalanine 85 and leucine 88 in other beta subunits. In low oxygen concentrations, multiple subunits bind and reduce the solubility of the polymeric beta subunits. addthis_url = location.href; addthis_title = document.title; addthis_pub = 'opensite';

66. Introduction: Sickle Cell Anemia - CureResearch.com Introduction to Sickle Cell Anemia as a medical condition including symptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis. http://cureresearch.com/s/sickle_cell_anemia/intro.htm

Home About us Symptoms Symptom search ... Share your misdiagnosis story Introduction: Sickle Cell Anemia Sickle Cell Anemia: Genetic disease causing anemia from improperly formed red blood cells. Researching symptoms of Sickle Cell Anemia: Further information about the symptoms of Sickle Cell Anemia is available including a list of symptoms of Sickle Cell Anemia , other diseases that might have similar symptoms in differential diagnosis of Sickle Cell Anemia , or alternatively return to research other symptoms in the symptom center Misdiagnosis and Sickle Cell Anemia: Research more detailed information about misdiagnosis of Sickle Cell Anemia failure to diagnose Sickle Cell Anemia , or research misdiagnosis of other diseases Treatments for Sickle Cell Anemia: Various information is available about treatments available for Sickle Cell Anemia current research about Sickle Cell Anemia treatments , or research treatments for other diseases. Statistics and Sickle Cell Anemia: Various sources and calculations are available in statistics about Sickle Cell Anemia prevalence and incidence statistics for Sickle Cell Anemia , and you can also research other medical statistics in our statistics center Contents for Sickle Cell Anemia: Basic Summary for Sickle Cell Anemia Prevalence and Incidence of Sickle Cell Anemia Prognosis of Sickle Cell Anemia Risk Factors for Sickle Cell Anemia ... Books about Sickle Cell Anemia Last revision: June 16, 2003

67. Kids And Teens - Health - Conditions And Diseases - Sickle Cell Anemia, Kids And sickle_cell_anemia. Kids and Teens Health - Conditions and Diseases - Sickle Cell Anemia. Sickle Cell Anemia is an inherited disease in which the red http://www.inter.co.yu/kategorije/Kids_and_Teens/Health/Conditions_and_Diseases/

Početna strana Magazin Adresar Sanovnik ... Inter Webmail Adress directorium Top Health Kids and Teens - Health - Conditions and Diseases - Sickle Cell Anemia Sickle Cell Anemia is an inherited disease in which the red blood cells change shape and cause small clots. It primarily affects people of African descent. Symptoms include joint and bone pain, feeling tired, shortness of breath, rapid heart rate, and sores on the legs. Sickle cell anemia also slows growth and can delay puberty. Treatments are used to help symptoms. They include folic acid to help build new red blood cells, antibiotics to manage infections, and wound care or surgery for ulcers on the lower legs. There is no cure. KidsHealth: Do You Know About Sickle Cell Anemia? [ Kids ] - Article tells how sickle cell gets its name, causes, symptoms, tests, and treatment. MedlinePlus: Sickle Cell Anemia [ Teens/Mature Teens ] - Illustrated article gives definition, causes, treatment, and risk factors. Sickle Cell Society [ Mature Teens ] - A UK-based charity which provides care and information. Site includes research findings, pain management techniques, and teaching resources. TeensHealth: Sickle Cell Anemia [ Teens/Mature Teens ] - Tells what the condition is, how it affects people, how it may be treated, and what young people can do to stay well.

68. Sickle Cell Anemia - Biocrawler, The Free Encyclopedia Retrieved from http//www.biocrawler.com/encyclopedia/sickle_cell_anemia . Categories Hematology Genetic disorders http://www.biocrawler.com/w/index.php?title=Sickle_cell_anemia&redirect=no

69. Sickle Cell Anemia Sickle Cell Disease is a genetic disorder of the blood. http://www.tylermedicalclinic.com/sickle_cell_anemia.htm

The Tyler Medical Clinic Assisted Conception - Affordable Infertility Treatments - List of Diseases - Sickle Cell Anemia Sickle Cell Disease is a genetic disorder of the blood, affecting approximately 72,000 individuals in the United States. It is characterized by anemia, frequent infections, and unpredictable and severe pains in the back, chest, abdomen and limbs. Sickle Cell Disease is most common among those of African descent. An estimated 8 to 12 percent of African Americans carry the sickle cell gene. It is also fairly common in people from Mediterranean countries, Middle East and India. Symptoms of Sickle Cell Disease may appear as early as in 6 months of age and include infections, pain and swelling of hands and feet, enlargement of the abdomen and heart. It is caused by a defective gene, producing an abnormal form of hemoglobin. Hemoglobin is the component of the red blood cell responsible for oxygen transport from the lungs to the tissues. Red blood cells do not retain their normal disc shape once they release oxygen, instead they take on a sickle shape. Their distorted shape makes it difficult for the red blood cells to pass through vessels, preventing oxygen and vital nutrients from reaching organs and tissues. This manifests into intense pain and patients also become vulnerable to infections. Blood flow to the brain may be affected and could lead to a stroke. Sickle Cell Disease is inherited as an autosomal recessive trait. Both parents must be carriers and each must pass on the sickle cell gene for the child to be affected. Individuals who carry the trait generally do not show any symptoms. A simple blood test can determine whether an individual is a carrier or not. People who are from an at risk population should be tested. Diagnosis of the disease itself is accomplished through a test called electrophoresis.

70. Sickle Cell Anemia Sickle Cell Anemia Sickle cell anemia is a common ailment in patients of African descent. This disorder is a very common reason for individuals to seek http://www.ringsurf.com/online/1227-sickle_cell_anemia.html

Home Rings Articles Contact Ring Login Forum Sickle Cell Anemia Home Write Health Mens Health Issues ... Sickle Cell Anemia Sickle Cell Anemia Sickle Cell Anemia Epidemiology Sickle cell disease chiefly is a disorder limited to individuals of African descent and Hispanics of Caribbean ancestry. However, the disorder is also common in the middle east, Latin America and in the Mediterranean countries. Millions of individuals worldwide suffer complications from sickle cell disease. Data from the US indicate that at least 2 million African-Americans have the sickle cell trait. The disease affects both genders equally. Despite all the innovations in therapeutics, the majority of the affected individuals do not survive past the age of 50. Causes Sickle cell is caused by a defect in the hemoglobin molecule. Hemoglobin is the compound which binds to oxygen and when hemoglobin is deformed, sickle cell anemia can occur. Individual who have sickle cell have their hemoglobin named as Hb S. The disease is inherited genetically- each parent donates one gene. An individual must have two genes to have the disease and if there is only gene present, the individual is a carrier of the disease. In order for sickle cell to be passed to the next generation, both parents must pass the defective gene to the child. However, because the gene is recessive (not dominant), the chance of a child having sickle cell anemia is 25%, there is a 50% chance that the child may be a carrier and 25% chance that the child may be normal.

71. Sickle-cell Anemia Definition | Define Sickle-cell Anemia | What Is It? Sicklecell Anemia meaning including Sickle-cell Anemia definition and what Sickle-cell Anemia actually means! http://www.biologyglossary.net/definition/2670-Sickle_cell_Anemia

Home E-Mail Latest Main Homepage Suggest Definition Browse By Term Latest Additions ... Contact Latest Info A configuration of... [View] Having non-identic... [View] The merger of clas... [View] Meaning between bl... [View] A chromosome havin... [View] The end of a polyn... [View] The characteristic... [View] An organism depend... [View] A branch of statis... [View] See repetitive DNA... [View] More Sites Sickle-cell Anemia What is it? Potentially lethal human disease, inherited as an autosomal recessive, caused by a mutation in a gene coding for the beta subunit of the oxygen-transporting protein haemoglobin. Under conditions of low oxygen tension, the altered beta-globin molecule causes haemoglobin to aggregate forming rod-like arrays that distort the cell membrane forcing red blood cells to become sickle-shaped. The sickled red blood cells are damaged and rapidly removed from the circulation causing anaemia. Added By: Leah The Sickle-cell Anemia definition has been viewed Time(s)! Send To Friends! If you'd like to send the Sickle-cell Anemia definition to yourself or to your friends/colleagues, just enter the e-mail addresses in the boxes below - We hope you now understand the meaning of Sickle-cell Anemia. If you need any more information on this term, please don't hesitate to contact us.

72. Verity K2 Document Display DTIC Thesaurus Entry. Descriptor SICKLE CELL ANEMIA Broader Terms ANEMIAS; Narrower Terms Used Alone For Use Used in Combination For http://stinet.dtic.mil/stinet/jsp/docread.jsp?K2DocKey=/stidataU2/descriptors/S/

73. Strony Www > Kids And Teens> Health> Conditions And Diseases> Sickle Cell Anemia Baza stron www. Start Kids_and_Teens Health Conditions_and_Diseases sickle_cell_anemia. KidsHealth Do You Know About Sickle Cell Anemia? http://www.cares.bia.pl/Kids_and_Teens/Health/Conditions_and_Diseases/Sickle_Cel

Baza stron www Start Health KidsHealth: Do You Know About Sickle Cell Anemia? [ Kids ] - Article tells how sickle cell gets its name, causes, symptoms, tests, and treatment. Medline Plus: Sickle Cell Anemia [ Teens/Mature Teens ] - Illustrated article gives definition, causes, treatment, and risk factors. Sickle Cell Society [ Mature Teens ] - A UK-based charity which provides care and information. Site includes research findings, pain management techniques, and teaching resources. TeensHealth: Sickle Cell Anemia [ Teens/Mature Teens ] - Tells what the condition is, how it affects people, how it may be treated, and what young people can do to stay well. Submit a Site Open Directory Project Webdesign firany ... Bilety lotnicze Volarweb

74. Aravol Dmoz - Directory :Kids And Teens:Health:Conditions And Diseases:Sickle Ce Top Kids_and_Teens Health Conditions_and_Diseases sickle_cell_anemia. All sites submitted to this category must be designed for use by kids / teens and http://dmoz.aravol.org/?type=desc&path=/Kids_and_Teens/Health/Conditions_and_Dis

75. Sickle Cell Anemia. Overview of sickle cell anemia, and how to treat it in a natural way. http://www.herbs2000.com/disorders/sickle_cell_anemia.htm

Welcome to herbs2000.com - Number one source of traditional and nutritional health care. HERBS - THE BASICS Actions of herbs Herbs for beauty Herbs for dogs ... H O M E Let herbs be your medicine and medicine be your herbs! Sickle Cell Anemia When the oxygen carrying capacity of the red blood cells is impaired it results in a condition known as anemia ; there are many reasons for anemia all of which describe this deficiency in the oxygen carrying capacity of the red blood cells within the body. Due to a genetic defect some individuals have red blood cells that are sickle or crescent shaped and this impairs the ability of the cells to carry oxygen leading to chronic anemia in a condition called sickle cell anemia-which is an inherited disorder in all individuals who suffer from it. Because of this peculiar shape, the red blood cells often clog the smaller of the blood vessels and this leads to an impairment of the oxygen varying capacity of the blood leading to the appearance of the symptoms typical of sickle cell anemia; thus a physical defect in the morphology of the cell leads to its inability in delivering oxygen. Due to this clogging on the blood vessels, there may be a severe deprivation of oxygen in the tissues and this leads to a sickle cell crisis; which is a painful episode physically manifested in the body of the individual. People of European descent rarely have this genetic defect and therefore the disorder or the particular genetic trait occurs mostly in people of African descent, and also in people from the Mediterranean countries, the Middle East and India, and the Middle East; the cause of this illness is genetic and therefore strictly inherited being passed from parent to child.

76. Sickle Cell Anemia Articles, Support Groups, And Resources Sickle cell anemia articles, support groups, and resources for patients from Med Help International (www.medhelp.org) http://www.medhelp.org/HealthTopics/Sickle_cell_anemia.html

place_direct_ad('http://media.medhelp.org/hserver/AAMALL/site=medhelp/area=health_topics/action=show/object_name=Sickle_cell_anemia/env=production',728, 90, 'leader'); place_direct_ad('http://media.medhelp.org/hserver/AAMALL/site=medhelp/area=health_topics/action=show/object_name=Sickle_cell_anemia/env=production',160, 600, 'skyscraper'); [Health Topics A-Z] A B C D ... Z Sickle cell anemia Medical Glossary: Sickle cell anemia Sickle cell anemia - resources Ask The Doctor Forums Henoch-Schonlein Purpura and Sickle Cell Anemia? [Childhood Disease] (Maternal and Child Health Forum) Sickle Cell Trait vs Sickle Cell Anemia [Pregnancy - Normal] (Maternal ~ Child Health Forum) What exactaly is Sickle Cell Anemia [Family Problems] (Mental Health Forum) place_direct_ad('http://media.medhelp.org/hserver/AAMALL/site=medhelp/area=health_topics/action=show/object_name=Sickle_cell_anemia/env=production',728, 90, 'anchor'); MedHelp.org subscribes to the HONCode principles of the Health On the Net Foundation Verify here Revised: 5/28/2008

77. Concerning Your Health... Sickle Cell Anemia The leading source for health and medical information. http://www.betterchem.com/health/full_index/sickle_cell_anemia.htm

Betterchem Health About My Drug Medical Encyclopedia ... Site Map View the full medical reference Find Organization Index Page red blood cells, sickle cell, red blood cells, red blood cells, multiple sickle cells, red blood cells, sickle cells, red blood cells, sickle, pappenheimer, formed elements of blood, blood cells, anemia, sickle cell, hemoglobin ss disease, hb ss, sickle cell disease, sickle cell anemia, inherited disease, the red blood cells, disc-shaped, become crescent shaped, function abnormally, small blood clots, clots give rise to recurrent painful episodes, "sickle cell pain crises", sickle cell anemia, an abnormal type of hemoglobin , hemoglobin s, hemoglobin, protein inside red blood cells that carries oxygen, hemoglobin s, reduces the amount, oxygen inside the cells, distoring their shape, fragile, sickle-shaped cells deliver less oxygen, body's tissues, and can break into pieces that disrupt blood flow, sickle cell anemia is inherited, an autosomal recessive trait, it occurs in someone who has inherited hemoglobin s from both parents, sickle cell disease is much more common in certain ethnic groups, affecting approximately one out of every 500 african americans, someone who inherits hemoglobin s, one parent, normal hemoglobin, a, other parent, have sickle cell trait , someone who inherits hemoglobin s, one parent, another type of abnormal hemoglobin, other parent, have another form of sickle cell disease, such as  thalassemia , sickle cell disease is present at birth, don't occur, after 4 months of age, sickle cell anemia, become life threatening, blocked blood vessels, damaged organs, cause

78. Sickle Cell Anemia Introduction. Sickle Cell Anemia is a genetic disorder that is characterized by the formation of hard, sticky, sickleshaped red blood cells, in contrast to http://bsw-uiuc.net/tutorials_current/Sickle_Cell_Anemia/SC2001/intro.html

79. LESSON PLANET: Teachers Find Online Lessons Fast! Search from over 150000 online lesson plans that are teacherreviewed and correlated to state standards. http://www.lessonplanet.com/search/Science/Biology/Genetics/Genetic_Diseases/Sic

home my account log in Teachers... Find Online Lessons Fast! Search from over 150,000 online lesson plans that are teacher-reviewed and correlated to state standards. Quickly search over 150,000 teacher reviewed online lesson plans. Rating 1+ Stars 2+ Stars 3+ Stars 4+ Stars 5 Stars Grades Pre-K K-2 Higher Ed Advanced Search Directory Home Science Biology ... Sickle Cell Anemia Lesson Plans Sickle cell anemia Lesson Plans (1 - 10 of 31): Gene Inheritance - Students explore how genes, including those that cause disease, are passed from one generation to the next. They explore the connection between an organism's genes and its traits. Overall Rating: Full Review >> Your Body, Your Health - Students review and discuss what they learned about sickle cell anemia. They explore other genetic disorders, and create a poster presentation to teach about a disorder. Overall Rating: Full Review >> Parasites: Our Tiny Companions - Students consider parasites that seek human hosts. They prepare nutrient agar plates and cultivate samples of bacteria taken from their own bodies. They experiment with disinfectants and soaps to determine which method kills the most bacteria. Overall Rating: Full Review >> Oops! I Made a Mistake

80. Nursing Research: Pain In Sickle Cell - From Medicine.org Nursing Research Pain in Sickle Cell For a child with sickle cell disease (SCD), an acute vaso-occlusive episode can be extremely painful, http://www.medicine.org/genetic_disorders/sickle_cell_anemia/nursing_research_pa

@import "misc/drupal.css"; @import url(modules/healthsavvy/fda.css); @import url(modules/googlesws/googlesws.css); @import url(modules/healthsavvy/hs_layout.css); @import "modules/event/event.css"; @import url(modules/eventfinder/eventfinder.css); @import url(modules/location/location.css); @import "themes/medicine2/style.css"; Help Contact Us Join Now Login ... Home Site Search: Home Genetic Disorders Sickle Cell Anemia News Nursing Research: Pain in Sickle Cell Submitted by Roxanne RN on Wed, 05/09/2007 - 4:50pm. On the day of admission, the most frequent medications given were morphine, ketorolac, and diphenhydramine, while other medications included acetaminophen, acetaminophen with codeine, amitriptyline, and hydromorphone. The administered doses of morphine were in the subtherapeutic to low therapeutic range in 85% of the cases. Doses of the other medications tended to be in the low therapeutic range. The average MQS score of medications prescribed on the first day of admission was 22, but the average score of the medications actually administered was 16, indicating suboptimal pain treatment despite high initial levels of pain intensity. Both the MQS scores and the pain scores decreased each day, and the average length of stay was 4 to 5 days. These findings indicate that the administered doses of pain medications are often subtherapeutic for children with SCD during an acute vaso-occlusive episode. Children in Pain From Sickle Cell Disease May Not Receive Adequate Pain Relief Jacob E, Miaskowski C, Savedra M, Beyer JE, Treadwell M, Styles L. Quantification of analgesic use in children with sickle cell disease. Clinical Journal of Pain. 2007;23:8-14.

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